The main objective of this study is to formulate and evaluate of Bioadhesive pulsatile drug delivery system of an antilipidemic drug. In order to achieve a improved therapeutic efficacy. The present research works describe the combination of Bio adhesive pulsatile principle are very suitable for site and time specific. Gastroretentive drug delivery is an approach to prolong gastric residence time, thereby targeting site specific drug release in the upper gastrointestinal tract (GIT) for local or systemic effects. Several gastro retentive drug delivery approaches being designed and developed...