Polycystic Ovary Syndrome (PCOS) is a heterogeneous multifactorial endocrine metabolic disorder affecting 6-10% of the reproductive age women. Common symptoms of PCOS include oligoanovulation, hyperandrogenism, acne, hirsutism, obesity, infertility and insulin resistance. Women with PCOS are reported to be at increased risk of number of gynecological neoplasias such as endometrial, breast and ovarian cancer. Tumor suppressor genes (TSGs) perform essential function in the maintenance of genomic stability. Single nucleotide polymorphisms (SNPs) are common DNA sequence variants among individuals...
Polycystic Ovary Syndrome (PCOS) is a heterogeneous multifactorial endocrine metabolic disorder affecting 6-10% of the reproductive age women. Common ...