AL-Thubiani, Wafa, Abuzinadah, Osama, Abd El-Aziz, Gamal
The therapeutic usefulness of Adriamycin (ADR), a potent anticancer drug, is restricted due to the development of certain side effects, the most dangerous being cardiotoxicity. This research focused on the possible protective effect of betanin (an active component of beetroots) and allicin (an active element of garlic) against ADR-induced cardiotoxicity in rats.Cardiac toxicity was induced in female Wistar rats with a single i. p. injection of ADR (15 mg/kg, i. p) on the 8th day. Hemodynamic characteristics of the cardiovascular system and electrocardiography (ECG) were evaluated.Betanin and...
The therapeutic usefulness of Adriamycin (ADR), a potent anticancer drug, is restricted due to the development of certain side effects, the most dange...