As we know the healthy periodontium, is affected in most periodontal diseases, which further leads to damage of hard and soft tissues. To attain back the lost structures the use of bone grafts has shown promising results. Managed either by mechanically re-contouring it or by grafting techniques. Replacement grafts are widely accepted as bone formation by promoting periodontal regeneration. There are many bone graft material which is used as a bone substitute to fill the defect site the graft material acts like a scaffold on which body react it by certain bone mechanism helps to regenerate new...