SummaryThe current searching for broad-spectrum, effective non-toxic, and inexpensive antibilharzial medications for schistosomes vaccination and treatment in developing countries is of great interest. In addition, effective specific medications in the management of schistosomiasis transmission to avoid the possibility of development of a drug-resistant strain of the parasite. As, toll-like receptor ligands, were previously found to have (antitumor and antiviral) activities, the present study was conducted to evaluate the adjuvant effect and anti-schistosomal activity of Poly(I: C)and Zymosan...