Malaria is a life-threatening tropical illness disseminate by an infected female Anopheles mosquito. If it isn't diagnosed and handled quickly, it can be disastrous. (Snow, Guerra, Noor, Myint, & Hay, 2005). Annual malaria mortality due to Plasmodium falciparum costs 1 to 2.7 million populates in Africa exclusively, most of them are young children's (Phillips, 2001). We have used in silico approach to design drugs for malaria.