Description:Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content. Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology of sperm DNA fragmentation (SDF), which affects both natural and assisted reproduction. Several clinical and environmental factors are known to negatively impact sperm DNA integrity. An...

The ESHRE Special Interest Group in Embryology published the Atlas of Embryology in 2000 as a supplement to Human Reproduction. This initiative was received with acclaim and has become a very valuable reference that is used by embryologists all over the world.We have undertaken to produce a new edition that completely updates the first edition and have chosen to publish it as an online document that provides the additional advantages of flexibility for revision and ease of consultation. The ease of online publication means that the Atlas can be updated on a regular basis and we intend, in the...