Objective: The study was designed to screen the protective effect of Vernonia cinerea extract against sunset yellow induced anxiogenic behaviour in mice through counteracting oxidative damage.Methods: The anxiogenic effect was induced by the administration of sunset yellow (20 mg/kg, p.o) for 30 days. Ethanol extract of Vernonia cinerea (EEVC) (400 mg/kg, p.o) administered, after 1 hour of sunset yellow treatment. Diazepam (1 mg/kg, p.o) was used as a reference drug.Results: FT-IR studies of the extract were done to determine the presence of phenols and flavonoids. Vernonia cinerea...