Vaccination is a process that induces specific immune resistance to a bacterial or viral infectious disease. Vaccines have prevented several infectious diseases for many years, and are still being investigated. Factors that have an impact on the trends of vaccine development include progress in translatory medicine, demographics, regulatory science, political, cultural, and social responses. They are generally prophylactic, i.e., they ameliorate the effects of future infection. One such vaccine considered here is the 'Periodontal Vaccine'.

Mast cells are found in all tissues of the oral cavity including dental pulp.Degranulation of mast cell releases proinflammatory mediators such as Tumor Necrosis factor-alpha, Chymase, Tryptase, Matrix Metalloproteinases (MMPs), Heparin, Histamine, various interleukins IL3, IL4, IL5, IL6, IL8, IL10, IL13,IL16 and cytokines contributing to the progress of periodontal disease.Thus the administration of locally or systemically acting mast cell stabilizer that inhibit mast cell degranulation may be a useful method to probe the role of mast cell in periodontitis.

L'objectif de la dentisterie moderne est de restaurer la structure de la dent de manière fonctionnelle et esthétique. Une nouvelle approche pour restaurer la structure dentaire est basée sur des procédures régénératives par l'application de l'ingénierie tissulaire. L'identification des cellules souches adultes a jeté une lumière sur la dentisterie régénérative et a permis de remplacer les structures endommagées. Les cellules souches ont le remarquable potentiel de se développer en de nombreux types de cellules différentes dans le corps. Elles servent de système de réparation...

The goal of modern dentistry is to functionally and cosmetically restore the tooth structure. One novel approach to restore the tooth structure is based on regenerative procedures by the application of tissue engineering. Identification of adult stem cells has thrown a light on regenerative dentistry and has provided insight to replace damaged structures.Stem cells have the remarkable potential to develop into many different cell types in the body. They serve as a repair system for the body. When a stem cell divides, each new cell has the potential to either remain a stem cell or become...

Das Ziel der modernen Zahnmedizin ist die funktionelle und kosmetische Wiederherstellung der Zahnsubstanz. Ein neuartiger Ansatz zur Wiederherstellung der Zahnstruktur basiert auf regenerativen Verfahren durch die Anwendung von Tissue Engineering. Die Identifizierung adulter Stammzellen hat ein neues Licht auf die regenerative Zahnheilkunde geworfen und Einblicke in den Ersatz geschädigter Strukturen gegeben.Stammzellen haben das bemerkenswerte Potenzial, sich zu vielen verschiedenen Zelltypen im Körper zu entwickeln. Sie dienen als Reparatursystem für den Körper. Wenn sich eine...