Profound Local anesthesia is required to prevent pain during endodontic treatment of teeth with vital pulps. Incomplete anesthesia results in pain and increases the patient's anxiety, with a concomitant drop in their pain threshold. A wide variety of anesthetic drugs are available for dental use. The practicing dentist should have a sufficient selection of anesthetic solutions to meet every situation. One of the prime considerations in the selection of a local anesthetic is the approximate duration for which analgesic effect is required. Of the four sympathomimetic amines commonly used as...