Periodontitis is a chronic inflammatory disease, characterized by gingival bleeding, periodontal pocket formation connective tissue destruction, and alveolar bone resorption leading to tooth loss. Mitochondria are the intracellular organelles that play a significant role in the cells by metabolizing nutrients and producing the "energy currency" adenosine triphosphate (ATP) and are responsible for various processes.Mitochondrial dysfunction has been defined as the inability of mitochondria to sustain ATP synthesis sufficient to satisfy cellular demands.Periodontopathic bacteria in the...