This volume collects revised versions of some of the papers presented at the S- ond IST/FET International Workshop on Global Computing held in Rovereto, Italy (9 12 March, 2004). The workshop involved all the thirteen projects funded under the IST/FET proactive initiative on GLOBAL COMPUTING: AGILE; CRESCCO; DART; DBGLOBE;DEGAS;FLAGS;MIKADO;MRG;MYTHS;PEPITO;PROFUN- DIS; SECURE; SOCS. The ?rst aim of the GLOBAL COMPUTING initiative is the development of paradigms for building ?exible, dependable, secure, robust and e?cient systems. Primaryresearchconcernsaretheco-ordination, interaction,...

The goal of the IST/FET proactive initiative on Global Computing is to - tain models, frameworks, methods, algorithms to build systems that are ?exible, dependable, secure, robust and e?cient. The dominant concerns are those of handling the co-ordination and interaction, security, reliability, robustness, fa- uremodes, andcontrolofriskoftheentitiesinthesystemandtheoveralldesign, descriptionandperformanceofthesystemitself.Completelydi?erentparadigms of computer science may have to be developed to tackle these issues e?ectively. The research should concentrate on systems having the following...

The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. This special issue of the journal focuses on the topic of modeling methodologies. It starts with a position paper by the guest editors, entitled Biomodel Engineering from Structure to Behavior, which is followed by the technical...