Volume 40 of "Progress in Drug Research" contains six reviews and the various indexes which facilitate its use and establish the connec- tion with the previous volumes. The articles in this volume deal with phosphodiesterase inhibitors and their therapeutic potential in asthma; peptide receptor ligand drugs; aldose reductase inhibitors; the design and discovery of new drugs by stepping-down and stepping-up approaches; new synthetic ligands for L-type voltage- gated calcium channels and with luteolytic agents in fertility regula- tion. III the 33 years that "Progress in Drug Research" has...

Volume 41 of "Progress in Orug Research" contains eight reviews and the various indexes which facilitate its use and establish the con- nection with the previous volumes. The articles in this volume deal with teratogenesis; nephrotoxicity; bacterial resistance to P. lactam antibiotics; eradication of diseases by vaccination; chirality and drug design; endogenous digitalis-like factors; erythropoietin; and sero- tonin (5HT)-antagonists. 3 All these articles give an excellent overview of the respective fields of research. In the 33 years that POR has existed, the Editor has enjoyed the valu-...