Globalization is affecting regional economies in a broad spectrum of aspects, from labor market conditions and development policies to climate change. To understand better how this works, we need both conceptual and methodological contributions. We need new schemes to organize our thinking, direct our attention, and frame thought experiments on the basis of which guidance may be offered. And we need methodological innovations that enable us to carry out studies and thought experiments at levels of spatial and temporal resolution and formal complexity adequate to capture and account for the...