Diagnosis of meningococcal disease is essential for institution of early treatment to reduce the mortality and complications of this serious infection. This work explores and covers cultural and non-cultural techniques on cerebrospinal fluid (CSF) or blood specimens from persons suffering from meningococcal disease. Non-cultural techniques for the diagnosis of the disease in this work included common serological tests for the detection of anti-meningococcal antibodies or bacterial antigens in cerebrospinal fluid. With rapid antigen detection methods include Co-agglutination (COA) and latex...