Cystic fibrosis is a serious inherited disease which mainly affects the lungs and pancreas, but can involve other organs. Symptoms usually begin in early childhood and include persistent cough, wheeze, repeated chest infections, malabsorption of food, and general ill health. The cystic fibrosis is cause by due to environmental and genetical factors. Ireland has the highest ratio of cystic fibrosis in the world; 2.98 per 10,000 - and the highest carrier rate in the world with 1 in 19 individuals classed as carriers. It can be Diagnosis by Sweat test, Genetic test, Screening test. There are...

This study was carried out to observe inter-strain variation at molecular level in the two vaccinal types (B: 3, 4 and B: 6). The 85, 27 kDa major and 70 and 40 kDa minor proteins run on SDS-PAGE were common in both strains. The 50, 32 and 29 kDa major proteins were found in B: 3, 4 but absent in B: 6. SDS-PAGE profiles of outer membrane protein (OMP) showed that 26 minor bands were common. The 50 and 32 kDa major protein were found in B:3,4 and absent in B:6, while 46kDa minor protein was found in B:6 only. The spectral peaks of whole cells, envelope and OMPs could be differentiated between...