Vaccine research in periodontal diseases is still in its infancy. The complexities in the etiopathogenesis of the periodontal diseases have been the prime obstacle in the hunt for vaccine. Among some 300 species of bacteria involved in subgingival plaque, 5-7 species have been implicated in the etiology of periodontitis which might play an important role as primary pathogens. A new milestone was achieved after the prime pathogens, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, were implicated in the etiology of periodontal disease. Now, vaccine research has shifted toward...
Vaccine research in periodontal diseases is still in its infancy. The complexities in the etiopathogenesis of the periodontal diseases have been the p...
La recherche de vaccins contre les maladies parodontales en est encore à ses débuts. La complexité de l'étiopathogéniedes maladies parodontales a été le principal obstacle à la recherche d'un vaccin.Parmi les quelque 300 espèces de bactéries présentes dans la plaque sous-gingivale, 5 à 7 espèces ont étéimpliquées dans l'étiologie de la parodontite et pourraient jouer un rôle important en tant qu'agents pathogènes primaires.Une nouvelle étape a été franchie après que les agents pathogènes primaires, Porphyromonas gingivaliset Actinobacillus actinomycetemcomitans, ont...
La recherche de vaccins contre les maladies parodontales en est encore à ses débuts. La complexité de l'étiopathogéniedes maladies parodontales a...
Die Impfstoffforschung bei Parodontalerkrankungen steckt noch in den Kinderschuhen. Die Komplexität der Ätiopathogenesevon Parodontalerkrankungen war das Haupthindernis bei der Suche nach einem Impfstoff.Von den etwa 300 Bakterienarten, die in der subgingivalen Plaque vorkommen, wurden 5-7 Artenmit der Ätiologie der Parodontitis in Verbindung gebracht, die als primäre Krankheitserreger eine wichtige Rolle spielen könnten.Ein neuer Meilenstein wurde erreicht, nachdem die wichtigsten Erreger, Porphyromonas gingivalisund Actinobacillus actinomycetemcomitans, in die Ätiologie...
Die Impfstoffforschung bei Parodontalerkrankungen steckt noch in den Kinderschuhen. Die Komplexität der Ätiopathogenesevon Parodontalerkrankungen wa...
Periodontitis is commonly observed and is an important concern in dental health. It is characterized by a multifactorial etiology, including imbalance of oral microbiota, mechanical stress, and systemic diseases such as diabetes mellitus. The current standard treatments for periodontitis include elimination of the microbial pathogen and application of biomaterials for treating bone defects. However, the periodontal tissue regeneration via a process consistent with the natural tissue formation process has not yet been achieved. Developmental biology studies state that periodontal tissue is...
Periodontitis is commonly observed and is an important concern in dental health. It is characterized by a multifactorial etiology, including imbalance...
It is well established that the periodontally diseased root surface does not favor regeneration of the periodontium due to its surface characteristics. Demineralization has been shown to alter the diseased root surface, creating a more acceptable surface that can influence events in wound healing. The in vivo and in vitro studies clearly indicate a greater potential for cell and fiber attachment to demineralized root surfaces. Other factors such as spatial relationships and wound stabilization may also impact the extent and predictability of periodontal wound healing following root surface...
It is well established that the periodontally diseased root surface does not favor regeneration of the periodontium due to its surface characteristics...
Antimicrobial peptides (AMPs), also called host defense peptides (HDPs) are part of the innate immune response found among all classes of life. AMPs have a broad spectrum of targeted organisms ranging from viruses to parasites. In this book we have tried to summarize the major types of AMPs, their modes of action, and the common mechanisms of AMP resistance along with the principles for designing effective AMPs and the future potential of using AMPs in periodontology.
Antimicrobial peptides (AMPs), also called host defense peptides (HDPs) are part of the innate immune response found among all classes of life. AMPs h...
