In this book, we study optimization models for health care under uncertainty and resource constraints. In particular, we study two problems. The first problem is the multi-shift Vehicle Routing Problem (MSVRP) with overtime to meet around-the-clock demand. We use insertion to create the initial routes and then use tabu search to improve the routes. We show that our algorithm can find high-quality solutions for very large problems. The second problem is a multi-city resource allocation model to distribute the medical supplies in order to minimize the total number of fatalities in an infectious...