As the aquaculture industry expands, its environmental impacts increases. The high nutrient discharges from aquaculture deteriorate the receiving water body. The dependence to fish oil and fishmeal for artificial feed has been threatened the world fisheries resources. Bio-flocs technology (BFT) application in aquaculture offers a solution to both problems. In BFT excess nutrient in aquaculture systems is converted into microbial biomass, which can in situ be used by the cultured animals as food source. The transmission of aquatic animal diseases is another major problem in aquaculture...