Ageing is a syndrome of changes that are deleterious, progressive, universal & thus irreversible. SIRT1 gene is a candidate gene, involved in ageing process. The SIRT1 gene, whose activity is modified by the body's metabolic state & was previously known to help control the process of ageing and extend the lifespan of humans, also plays a key role in regulating the internal clock. This important discovery helps to explain how the body regulates essential functions such as hormone production, body temperature & blood pressure, & may eventually lead to drugs to combat metabolic disorders,...