Andrographolide is the main diterpenoid lactone contained in the leaves of Andrographis paniculata. This bioactive component has multifunctional medicinal properties such as activity against fever, dysentery, diarrhoea, inflammation, cancer and sore throat as well as immune disorder. No solvent is ideal for the extraction of Andrographolide, however we can consider 60% methanol for the model development. Cancer is the largest single cause of death in both men and women, claiming over 6 million each year in the world. CML accounts for about 20% cases of adult and childhood leukemia....