Increasing incidences of antimicrobial resistance are proving to be a menace for the society. There is a demand for the synthesis of some new antimicrobial agents which can overcome this problem. In the present study, a series of pyridosulfonamide derivatives have been synthesized, to exploit the combined potential of pyridine and sulphonamide nuclei. Different derivatives were synthesized through a three step process. The success of syntheses was confirmed through physical and spectral characterization on the basis of IR spectroscopy, Mass spectrometry and PNMR spectroscopy. These...