The House of Santos is a family saga, filled with characters who people the US western landscape in the Arizona territory from 1822–1898. The House of Santos grows from three families who join together to create a heritage from their strengths, love, and ambitions. They have a passion for life, for moving forward, and for growing as they change. If they fulfill their dreams, it is because of their human endurance, love, understanding, and stubborn striving for success and stability.