Generalized anxiety disorder (GAD) is a prevalent and impairing disorder, associated with extensive psychiatric and medical comorbidity. The current pharmacotherapies of anxiety are based on antidepressants and benzodiazepines. However, these drugs have limitations like slow onset of action, development of drug dependence, tolerance, amnesia and sedation. Therefore, the use of alternative therapies has increased substantially over the last decade. Kava is an intoxicating beverage made from the root extract of Piper methysticum and has been known as anxiolytic drug. The German health...