Ceramide are family of lipid molecules. Ceramide consist of a Long-chain or Sphingoid base linked to a fatty acid via an amide bond. Ceramide has emerged as a key regulator of a wide spectrum of biological processes such as cellular differentiation, proliferation, programmed cell death (PCD), and apoptosis of cells. Cell proliferation studies were carried out in chemically induced rat hepatocarcinogenesis. Immunostaining of PCNA, Ki-67 and BrdU results revealed that, Group C rats showed a minimal PCNA expression, decrement in ki-67 expression and Low BrdU labeling suggesting the suppressive...
Ceramide are family of lipid molecules. Ceramide consist of a Long-chain or Sphingoid base linked to a fatty acid via an amide bond. Ceramide has emer...