Human immunodeficiency virus related kidney disease is one of the leading causes of death and affects predominantly people of black descen. A cohort study was carried out at the Nylon District Hospital Douala, Cameroon to investigate the Kidney function trends amongst HIV seropositive individuals. Kidney function tests like serum urea, serum creatinine, creatinine clearance, proteinuria and urine chemistry was measured amongst 329 participants amongst whom 30.4% were HIV negative and 69.6% were HIV positive. The age range of the study population was 18 to 60 years. There were 94(28.6%) males...