The retina is a highly ordered laminar structure, comprising three compact layers of neurons separated by two synaptic layers, which has proven a valuable model to study gap junctions and cell specific expression patterns of connexins in neuronal tissues. Visual processing in the retina information is partly accomplished by laterally orientated horizontal cells. Two connexins, Cx52.6 and Cx55.5 has been shown to be expressed in zebrafish horizontal cells. Sequence analysis of zfCx55.5 and zfCx52.6 has revealed only limited homology of these connexins to other connexins from fish and higher...