The present research works carried out with the aim to prepare suspension dosage form using these microparticles for oral use. Solid Dosage forms are difficult for Pediatric, Geriatric patient & Dysphasic patients so for that patients the suspension dosage form more favorable than other solid dosage form. Albendazole drug has poor oral bioavailability (>5%) & a delayed release microspheric suspension of this drug would improve patient compliance & ease of swallowing. Microencapsulate facilitate the targeting of drug & mask the metallic taste of drug. The % yield was higher in the solvent...
The present research works carried out with the aim to prepare suspension dosage form using these microparticles for oral use. Solid Dosage forms are ...
Allopurinol is poorly water soluble drug used in treatment of gout. Rapid onset of action of allopurinol drug in treatment of gout is required. Solubility is rate limiting step for this drug. To enhance the solubility here solid dispersion and crystal engineering approach was selected and applied. The solubility and dissolution rate of allopurinol can be enhanced by the use of SDs of allopurinol with PVPK30. The solubilization effect of PVPK30, reduction of particle aggregation of the drug, absence of crystallinity, and alteration of the surface properties of the drug particles might be...
Allopurinol is poorly water soluble drug used in treatment of gout. Rapid onset of action of allopurinol drug in treatment of gout is required. Solubi...