Root biomodification is a treatment procedure employed for periodontal regeneration that uses acid substances or chelating agents to remove the smear layer and expose root collagen fibers. Such treatment enlarges dentinal tubules into which healing connective tissue can enter. Various agents have been employed in the past to achieve suitable results. Through this book, the author wants to draw the attention of both dental clinicians as well as patients towards the therapeutic potential of Doxycycline HCl in root biomodification. Doxycycline is believed to enhance maturation and...

Regeneration of supporting tooth structures is a huge step in managing periodontal defects and preventing tooth loss. These defects have been shown to be at higher risk of disease progression in subjects who had not received systematic periodontal therapy. These bony lesions may not be readily accessible to periodontal debridement, often requiring access flap surgery alone or in combination with bone resective techniques or regenerative procedures . Different modalities of regenerative treatment have been developed. Amongst these, grafting of biomaterials and application of biological...