HLA-B27 is a class I surface antigen encoded by B locus in the Major Histocompatibility Complex (MHC) on the short (p) arm of chromosome no.6,presents microbial antigen to T cells. HLA B is a human gene that provides instruction for making a protein that plays a critical role in immune system.HLA-B27 is strongly associated with a certain set of autoimmune disease referred as the "Seronegative Spondyloarthropathies", a group of disorders that include Ankylosing Spondylitis (AS) and other inflammatory joint diseases. It has been found that 90% of patients with this rheumatic disease...