The structure, function, and composition of the basement membrane of glomerular capillaries of the mammalian kidney have been extensively studied, in light of the membrane's frequent involvement in renal diseases. A novel mathematical model, based on the Fiber Matrix Theory, was developed to describe the dynamics of permselectivity of the glomerular capillary barrier using mainly its hemodynamic and morphometric variables. The glomerular basement membrane was represented as a homogeneous 3D meshwork of fibers of uniform length (L ), radius (R ), and packing density (N v) and characterized by...