BRONJ is a rare but serious clinical condition caused by antiosteoclastic, antiangiogenic and anti human endothelial cell proliferation effects of Bisphosphonates which inhibit bone turnover. They are commonly developed in those patients who receiving either long term nitrogen containing IV BPs therapy alone or associated with invasive dental procedure. Therefore proper dental evaluations and receive necessary treatment prior to initiating IV BPs therapy is mandatory to limit this while manipulation of IV BPs dosing may be effective in reducing skeletal related events (SREs) and minimizing...