Interpretation of complex data generated from modern hyphenated analytical instruments presents a challenge to analytical chemists. This book concerns the application of chemometric methods to responses obtained from arrays of planar microfabricated chemical sensors designed to respond reversibly to multiple volatile organic compounds (VOC). It addresses critical modeling and data analysis functions needed to guide the design and implementation of novel meso-scale and micro-scale instrumentation incorporating such arrays, which is intended for use in monitoring human exposures to complex VOC...