Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a...