Inflammation is one of the biggest challenges in current medicine. Glucocorticoid-based therapy is still the most commonly used treatment to combat chronic and acute inflammation. However, as this treatment is burdened with a detrimental side effect profile and the occurrence of glucocorticoid resistance, research efforts are focused on characterizing the anti-inflammatory mechanisms of glucocorticoids and developing new therapeutic strategies to fight inflammation. In this book, focus is put on the effects of the glucocorticoid receptor on NF-kB and NF- B-driven gene expression. The...