Concern has been expressed over the past decades about the potential deleterious effect of both syn- thetic and natural estrogenic endocrine disruptor in the environment on the male reproductive tract including sperm quality in wildlife species and humans alike. Moreover, there is a paucity of knowledge on the mechanisms of action of sesame and other phytoestrogens in male reproductive tracts. However, most works on phytoestrogens have focused on iso- flavones and lignans from soy-based andflaxseed meals Sesame plant is an annual herbaceous oil seed plant known to man since the ...