Image guided orthopedic intervention has seen rapid development in the past two decades. In many applications, the intraoperative use of medical imaging data has increased the safety and robustness of the surgical outcome. However it has also increased the applied radiation dose. Navigation systems were introduced in order to reduce the invasiveness of such procedures, while increasing the accuracy and safety of the procedures. The clinical procedures are often complex. Newly introduced systems often add more complexity and are not smoothly integrated into the clinical workflow. This book...