S-Nitrosothiols (RSNOs) are related to a variety of nitric oxide (NO)-dependent physiological processes such as vasorelaxation and anti-platelet activity. Recent studies view RSNO deficiency in blood as an indicator of endothelial dysfunction associated with cardiovascular diseases. Most assay techniques for RSNOs require extensive sample preparation steps and complex measurement systems. Further, no analytical methods exist that allow direct measurement in whole blood samples. This book describes, for the first time, the development of new electrochemical sensor for real-time blood RSNO...