What is life? What type of system is life? How can we understand life? Or what does "understanding life" really mean? Sixty years since the publication of What Is Life? by Schrodinger ] and after the rise and success of molecular biology, have we reached the answer to these questions? In the recent years, I have often been asked by young researchers and students in biology: "I am afraid that such basic questions on a life system itself are not answered by the main-stream approach of c- rent biology that elucidates molecules and genes. We need some alternative approach....