This Technical Brief summarizes the information that is currently available from scientific research on Endocrine Disrupting Compounds (EDCs), sometimes known as hormonally active agents. It was prepared in response to concerns over the potential for EDCs to enter the environment in treated wastewater and reuse of biosolids. This document provides a primer on the endocrine system, the nature and sources of EDCs, and their potential effects on human health and the environment. The potential for man-made chemicals to cause endocrine disrupting effects came to light as early as the 1960s. The...