Breast cancer is often initiated by abnormal cellular mechanisms and damage to DNA brought about by different types of cellular stress. This book reviews the current standards of pathological assessment of breast cancer specimens. There is a discussion of recent molecular profiling studies in breast cancer and how our view of the classification of breast cancer is changing. The current role of molecular tests in the management of breast cancer is also addressed, highlighting their strengths and limitations. Additionally, it is widely acknowledged that the extracellular matrix (ECM) of...