Brucellosis is one of the most important zoonotic diseases worldwide. This book focuses on host natural resistance and innate immunity against Brucella infection. The impact of Johne's disease, a chronic, granulomatous enteritis of ruminants and some wild-type species is examined as well. In addition, the molecular and cellular mechanisms of DNA vaccines are addressed in this book, as well as the optimization strategies that are currently pursued to harness the therapeutic and commercial advantages of DNA vaccination. Moreover, immune responses may substantially differ between conventional...