Breast cancer is characterised by the accumulation of genetic alterations, including point mutations and loss of entire DNA regions ("loss of heterozygosity" or LOH). Among genes that are affected by such events, the "tumour suppresser genes" (TSGs) have a

The study of MicroRNAs, or miRNAs is a field that could considerably change our vision of breast cancer biology. This book offers insight into our knowledge of human miRNAs, with a specific interest for breast cancer.

Breast cancer is the most frequently diagnosed type of cancer and a second leading cause of cancer death in women after lung cancer. This title describes nearly 150 drugs that are used in routine therapy or are in clinical trials in breast cancer patients, ranging from the classical tamoxifen, fluorouracil, to the ixabepilone, and lapatinib.

Breast cancer is the most frequently diagnosed type of cancer and the second leading cause of cancer death in women after lung cancer. It is estimated that breast cancer affects more than 1,000,000 women worldwide each year, and about 450,000 die from the disease. During the last decades, breast cancer has received considerable attention, yet it is a very old disease that was described years and years ago. This book provides a summary of breast cancer history. It covers the ages from the ancient times to the early 2000's, but mainly focuses on the 20th century and its numerous discoveries and...