This book is divided into two parts. The first part is about non-redundant clustering and feature selection for high dimensional data. The second part is on applying learning techniques to lung tumor image-guided radiotherapy. In the first part, a new clustering paradigm is investigated for exploratory data analysis: find all non-redundant clustering views of the data. Also a feature selection method is developed based on the popular transformation approach: principal component analysis (PCA). In the second part, machine learning algorithms are designed to aid lung tumor ...