Here are the proceedings of the 2nd International Conference on Advanced Data Mining and Applications, ADMA 2006, held in Xi'an, China, August 2006. The book presents 41 revised full papers and 74 revised short papers together with 4 invited papers. The papers are organized in topical sections on association rules, classification, clustering, novel algorithms, multimedia mining, sequential data mining and time series mining, web mining, biomedical mining, advanced applications, and more.