In this thesis, the author introduces various bio-inspired smart nanochannel systems. A strategy for design and preparation of novel artificial responsive symmetric/asymmetric single nanochannel systems under various symmetric/asymmetric stimuli is presented for the first time. The author's research work utilizes ion track etching polymer nanochannels with different shapes as examples to demonstrate the feasibility of the design strategy for building novel artificial functional nanochannels using various symmetric/asymmetric physicochemical modifications. The development of these nanochannels...