For the past several centuries, the evolution of dentistry has largely focused on the removal of diseased dental tissues, at ever-increasing bur rotation speeds, in the preparation of a cavity whose shape was dictated by the limitations of the current restorative material. Unfortunately, this indiscriminate removal of both decayed & healthy tooth structures was a corollary development. Hence, Recognition, control and elimination of the disease are the prime essentials in modern conservative, Minimal intervention dentistry. In the absence of disease, the concept of 'extension for prevention'...

Malaria is one of the most common diseases in developing countries and poses a great challenge to world health. Resistance of malaria parasites to available antimalarial drugs remains the main challenge to the effective control of the disease. The physiological conditions prevailing with in the acidic digestive vacuoles of the malaria parasites provide a suitable physiochemical environment for conversion of heam to beta-hematin/hemozoin. Though the both protein as well as lipids mediated beta-hematin formation remain valid hypothesis but later seems to be more relevant, when mechanism of...