The section of this handbook has been dividing into two volumes, the first volume contains information relating to purines, pyrimidine and nucleoside, oligonucleotide, polynucleotides, and their derivatives. Both ribo and deoxyribo compounds are listed also. The second volume will contain the remaining material similar to Volume 1 and material more relative to genetic and biological aspects such as enzymes involved in nucleic acid function, protein synthesis, linkage maps.

This volume contains information on the nucleotide composition of bacterial DNA. Eukaryotic protists, etc.; Nearest neighbour frequencies in DNA; repeated and unique sequences in eukaryotes; nucleic acid sequences in bacteriophage, chloroplasts, mitochondria, kinetoplasts, satellites and TRNA. Information on the physical properties of RNA, atomic coordinates of DNA-DNA. Also included in this volume is information on enzymes involved in nucleic acid function.

This first volume contains data on amino acids which consists of the coefficients of solubility in water, heat capacities, entropies of formation, and heats of combustion. Specific gravity liquids, sucrose solution, CsCI solution isokinetic glycerol and sucrose gradients for density gradient centrifugation and the temperature dependence for select compounds are included.