Phosphatase and tensin homolog (PTEN) belong to the group of gatekeepers tumour suppressor genes and is involved in multiple mechanisms leading to cellular defense against neoplastic transformation and progression. PTEN expression in feline and canine mammary gland tissues was investigated setting up an immunohistochemical method. Twenty four dogs and 17 cats were submitted to a two-years follow-up and clinico-pathological features were recorded and compared with immunohistochemical PTEN expression. PTEN-negative status occurred in 33% of canine and 76% of feline mammary carcinomas. In canine...

A concise and practical visual guide to normal cell identification for all those dealing with cytology in the dog and cat.

Normal Cell Morphology in Canine and Feline Cytology takes a uniquely visual approach to normal cell identification in dogs and cats. Single–page presentations offer vivid snapshots of particular cell types, with high quality microphotographs matched with annotated schematic diagrams and accompanying explanatory text. Providing a vital understanding of what normal cells look like, this text is ideal for all those in small animal veterinary...