This monograph consists of five chapters that describe the diagnosis and treatment of oral squamous cell carcinoma (OSCC), which is the most common malignant epithelial neoplasm affecting the oral cavity. Chapter One deals with different potentially malignant disorders in the development of OSCC, diagnostic methods of OSCC, the pertinence of biomarkers in OSCC therapy, classification of biomarkers, existing biomarkers in different stages of OSCC and the challenges of developing new biomarkers. Chapter Two is focused on principles, systems, technologies, therapeutic approaches, safety and...